Ask your doctor or pharmacist for more details. Patients with a history of anaphylactoid reactions to tramadol and other opioids may be at increased risk and therefore should not receive Tramadol hydrochloride and acetaminophen tablets. The effect of Tramadol hydrochloride and acetaminophen tabletsif any, on the later growth, development, and functional maturation of the child is unknown.
Follow patients receiving Tramadol hydrochloride and acetaminophen tablets and any CYP2D6 inhibitor for the risk of serious adverse events including seizures and serotonin syndrome, signs and symptoms that may reflect opioid toxicity, and opioid withdrawal when Tramadol hydrochloride and acetaminophen tablets are used in conjunction with inhibitors of CYP2D6 [see Drug Interactions 7 ].
Cranbury, NJ www. Withdrawal also may be precipitated through the administration of drugs with opioid antagonist activity e. In single-dose studies in acute pain, two tablets of Tramadol hydrochloride and acetaminophen tablets administered to patients with pain following oral surgical procedures provided greater relief than placebo or either of the individual components given at the same dose.
Though it helps many people, this medication may sometimes cause addiction. This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses.
The possible side effects of Tramadol hydrochloride and acetaminophen tablets are: Search Results Search Again. Enter the imprint code that appears on the pill e.
These doses are approximately 0.
Hydrochlorothiazide and Triamterene Strength: In contrast, acetaminophen tested positive for induction of sister chromatid exchanges and chromosomal aberrations in in vitro assays using Chinese hamster ovary cells. After stopping a CYP3A4 inducer, as the effects of the inducer decline, the tramadol plasma concentration will increase [see Clinical Pharmacology Warning Signs of Type 2 Diabetes.
Parenteral drug abuse is commonly associated with transmission of infectious diseases such as hepatitis and HIV. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof.
A slight but statistically significant increase in two common murine tumors, pulmonary and hepatic, was observed in an NMRI mouse carcinogenicity study, particularly in aged mice. How Much is Enough?
No drug-related teratogenic effects were observed in the progeny of rats treated orally with tramadol and acetaminophen. Metabolism and nutrition disorders — Cases of hypoglycemia have been reported very rarely in patients taking tramadol.
The Effects of Multiple Sclerosis. Like Us Follow Us. Serotonergic Drugs Clinical Impact: