A more powerful vasodilator such as nitroglycerin may be needed to control pain once it starts.
Half-life is 5—12 hours with chronic dosages. Other side effects include: This has led to their use in treating high blood pressure and angina pectoris. Blockers K ATP -specific: Retrieved 29 December Amiodarone Bretylium Quinidine Verapamil.
By relaxing the tone of this smooth muscle, calcium channel blockers dilate the blood vessels.
The most common side effect of Verapamil is constipation 7. Common side effects include headache, low blood pressurenauseaand constipation.
Annual Review of Pharmacology and Toxicology. Verapamil is used for controlling ventricular rate in supraventricular tachycardia and migraine headache prevention. Views Read Edit View history.
Verapamil can be given postoperatively in rabbits which have suffered trauma to abdominal organs to prevent formation of these adhesions. Retrieved 9 November American Journal of Neuroradiology. Ranolazine Antiarrhythmics class I: Plasma, serum, or blood concentrations of verapamil and norverapamil, its major active metabolite, may be measured to confirm a diagnosis of poisoning in hospitalized patients or to aid in the medicolegal investigation of fatalities.
It does not appear to be significantly teratogenic. Journal of clinical pharmacology.
Acute overdose is often manifested by nausea, asthenia, bradycardia, dizziness, hypotension, and cardiac arrhythmia. It is also used in fluorescent cell sorting for DNA content, as it blocks efflux of a variety of DNA-binding fluorophores such as Hoechst Journal of Labelled Compounds and Radiopharmaceuticals. Archived PDF from the original on 13 December International Drug Price Indicator Guide.