The studies produced no evidence of teratogenic activity. Brand names of combination products. Avoid drinking tonic water. If clinical improvement is not observed after treatment with 16 mg per day for at least 10 days, symptoms are unlikely to be controlled by further administration.
National Brand Equivalent (NBE) - Imodium®
The average daily maintenance dosage in clinical trials was 4 to 8 mg two to four capsules. If vomiting has not occurred, gastric lavage should be performed followed by administration of gms of the activated charcoal slurry through the gastric tube. Do not use Imodium to stop the diarrhea unless your doctor has told you to. Nonprescription over-the-counter usually is taken immediately after each loose bowel movement but not more than the hour maximum amount described on the label.
Imodium loperamide slows the rhythm of digestion so that the small intestines have more time to absorb fluid and nutrients from the foods you eat. Most of these reports occurred in the setting of acute dysentery, overdose, and with very young children less than 2 years of age. Drink plenty of liquids while you are taking this medicine, to keep from getting dehydrated.
Studies in morphine-dependent monkeys demonstrated that loperamide hydrochloride at doses above those recommended for humans prevented signs of morphine withdrawal. Store at room temperature away from moisture and heat. To make sure this is the right treatment for you, before you start taking loperamide it is important that you speak with your doctor or pharmacist:. If vomiting has not occurred, gastric lavage should be performed followed by administration of grams of the activated charcoal slurry through the gastric tube.
Loperamide should be used with special caution in young children because of the greater variability of response in this age group. In case of accidental overdosage, consult a physician immediately. There have been isolated reports of toxic megacolon in AIDS patients with infectious colitis from both viral and bacterial pathogens treated with loperamide hydrochloride.
The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. Therefore, it is advisable to use caution when driving a car or operating machinery. However, in two studies that enrolled elderly patients, there were no major differences in the drug disposition in elderly patients with diarrhea relative to young patients.
The effect of saquinavir on loperamide is of less clinical significance. Having problems opening this PDF? Imodium is also used to reduce the amount of stool in people who have an ileostomy re-routing of the bowel through a surgical opening in the stomach.
Fluid and electrolyte depletion often occur in patients who have diarrhea. The peak plasma levels of loperamide were similar for both formulations. Loperamide hydrochloride capsules are contraindicated in patients with a known hypersensitivity to loperamide hydrochloride or to any of the excipients.
If the victim has collapsed or is not breathing, call local emergency services at If you buy any medicines, check with a pharmacist that they are suitable to take with your other medicines.